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SkinVive before and after

Your relationship with your spa med injector is the same as a colorist. You trust their expertise, they know your head, and when they recommend something new, you jump. As the ideal candidate — a 40-something woman with thirsty skin — my injector Anna Grancher, Clinical Director of SpaDerma in Chicago, offered me this treatment pro bono as education for her staff. And as your beauty editor, I couldn’t help but report it.

Juvederm, the makers of Botox, released SKINVIVE in the U.S. in September 2023, after years of success abroad. SKINVIVE is not a neurotoxin (like Botox) or a filler (like Juvederm), but more like a heavy-duty, long-lasting injectable moisturizer. The brand calls it “the first and only FDA-approved hyaluronic acid (HA) microdroplet injectable in the U.S. to improve skin smoothness of the cheeks.” 

How SkinVive works

We know that hydration impacts skin quality and the way lines and texture appear. Glycerol is important in hydration since it provides elasticity to the skin and helps to repair the epidermal barrier. Aquaporin-3 (AQP3) — a protein that facilitates the flow of water and glycerol into and out of cells — significantly decreases with age and environmental factors like sun exposure, causing skin dryness both in skin’s feel and appearance. When patients get SKINVIVE, their AQP3 increases, which means hydration within the dermis — which means plump and glowing skin.

Before SkinVive
After SkinVive

My experience with SkinVive

Anna graphed out my cheeks (pictured) and then injected each quadrant with a tiny poke of SKINVIVE’s hyaluronic acid and lidocaine for pain (as well as and butanediol diglycidyl ether (BDDE), a crosslinking agent used in hyaluronic acid-based dermal fillers). The procedure took a few minutes and didn’t hurt at all.

In about two weeks, I saw a bit of acne on my cheeks, which is typical for my sensitive skin after any treatment. Then in roughly four weeks, my cheeks plumped to a radiant glow, kind of like after you sleep for nine hours with your best overnight moisturizer — but without any effort. 

The craziest result to me isn’t the appearance, but the actual texture of my skin. I find myself constantly touching my cheeks because they’re so insanely soft, as if my skin were made of that peach-fuzz fabric you find on Squishmallows or Lululemon Softstreme fabric. I also noticed that my skin “behaves” better, which is one of the products selling points.

Should you get SkinVive?

In clinical trials, SKINVIVE patients reported improvement in skin’s smoothness, lines, hydration, and glow at the one-month mark, which lasted for six months. 85% of participants said that the overall aesthetic of their skin improved as well. This is all to say that positive results are in your favor.

The biggest blocker for me would be the cost. In Chicago, treatment starts at $650 (2 mL), and most patients will be at this amount.

In my opinion, if you have the means and desire, go for it. If instead you’re budgeting for your spa med procedures, you might opt for an injectable with more immediate and long-lasting results like filler, or for very obvious results like Botox.

This article was originally published here on The Midst Substack.

Read more of my skin care advice: 

Saying “yes” to Botox: Why most Gen X women don’t raise a brow 

Changing face: The truth about our skin before and during menopause


If you’re looking for skincare designed specifically for women in perimenopause or menopause, consider Alloy M4 Face Cream, with estriol. Read our review of M4 Face Cream.

I believe that beauty is in everyone. Everyone. I also know that the media and advertising have long been telling us to feel inadequate and to look “better.” That buying a red lipstick isn’t just a boost quicker than espresso — it’s a story of liberation, a color palette of inclusion, and a finger back at the male gaze. I bring this media literacy and feminist lens to the articles that I write and carefully curate. This is my angle. But we’ve come too far to not also have some fun. Along with a personal mission to empower women, I share a lifelong love affair with the beauty industry, where decades of dedication define my profile, both literally and professionally. I’m a self-taught makeup artist who refined her skills in the theater, on set, at the MAC counter, and with cancer survivors. Here, I’ve witnessed beauty’s power to transform. I also love to write. I studied journalism and received my MFA in writing from the School of the Art Institute of Chicago, where I founded the indie publication, PISTIL Magazine. Stories of beauty, fashion, health and even horoscopes comprise my bylines, along with a long run as Beauty and Editorial Director at Walgreens. Formerly Head of Content at The Midst, I’m now a freelance writer here, bringing that same feminist lens and editorial curiosity to stories about beauty, health, and midlife. I’ve also added yoga training to the mix. My love of beauty has grown to include a deeper curiosity about how we feel in our bodies, especially when those bodies start changing the rules. Menopause, movement, and the messy business of being a woman in midlife have become part of my story, and part of what I want to write about. I share my home in Chicago with my heart, my teenage son, and my rock, my partner. My longtime wish to rescue every senior pet in the city maxes out at two pups and a cat in our fabulous rental — a constant work of art with my obsessive rotation of vintage gems. So, what’s the best part of being in midlife? If I had to choose one thing: confidence. The unwavering confidence to live contentedly and share my truth without fear — because living authentically is the (very hard and) very real expression of beauty. Explore my portfolio at laurialocsmondy.com.

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