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Definition of Great Unfuckening

10 of our most popular stories of 2025

Kayla Barnes and her partner sitting in a home sauna

Longevity is kind of a big deal. What expert tips are โ€˜doableโ€™ for aging well?

Learn from Midi CEO Joanna Strober, Kayla Barnes, Dr. Julie Fratantoni, Aja Campbell, Dr. Matt Walker, and Roma Van der Walt

By Alexis Mera Damen

From biohackers chasing 150-year lifespans to influencers selling mushroom powders and IV drips, the internet is full of longevity โ€œexpertsโ€ promising to slow down aging โ€” if you just subscribe, inject, or buy now. At The Midst, weโ€™re not here for the BS. Weโ€™re here for what actually works โ€” and more importantly, what makes life feel worth living as we age.

The topic of longevity hits close to home for many of us who are caregiving for aging parents while also navigating our own midlife health shifts. Weโ€™re wondering: how do we age well, not just longer? What does it mean to invest in your future self in a way thatโ€™s sustainable, joyful, and attainable?

Weโ€™re asking these questions at a time when the U.S. population is older than ever. The number of Americans 65+ is projected to rise from 58 million in 2022 to 82 million by 2050 โ€” a 47% increase. Between 1980 and 2022, the median age of the population increased from 30 to 38.9, and one-third of U.S. states now have a median age over 40, with Maine and New Hampshire leading the way.


Ruck this way: What are the best weighted vests for women?

By Esther Sedgwick

I recently turned 40, learned all about perimenopause (the hard way), and went on a big health kick. I started walking with a weighted vest as part of my new regimen and got hooked. Itโ€™s honestly been the most enjoyable thing about adjusting to my new โ€œmidlife healthโ€ routine.

You might have come across the Instagram reels joking about wearing baggy-ass jeans that teenagers told you were cool. Trying to eat protein and creatine like itโ€™s a job, and strapping on a weighted vest for bone density. And while thatโ€™s all funny, itโ€™s no joke.

Iโ€™ve gone deep researching womenโ€™s health and longevity (like reading clinical trials on PubMed, crushing hundreds of hours of podcasts, and ordering the clinicianโ€™s guidebook from the Menopause Society). A consistent finding has stood out in terms of how we can live in good health, for longer.


Alloy M4 Face Cream

Does estriol face cream work for women in perimenopause and post-menopause?

By Lauria Locsmondy

When youโ€™re approaching or in the thick of the collagen-sucking phase of life called menopause, buttering up your face with estrogen does wonders. At least thatโ€™s what many new meno brands, including pioneer Alloy, want us to believe.

But does this topical hormone, commonly used to treat vaginal dryness for GALs our age, actually work in skin care? Staying true to my beauty-editor roots, I figured thereโ€™s only one way to find out โ€” so, I tried Alloyโ€™s M4 Face Cream for three months.


a photo of Kristin Davis in a hotel room

Letโ€™s talk about Kristin Davisโ€™ filler removal

Is dissolving injectables the next big beauty trend?

By Bonny Osterhage

Criticized in the past for her puffy, โ€œoverfilledโ€ face and lips, actor Kristin Davis has embraced a more natural look after having her fillers dissolved. โ€œI have done fillers and itโ€™s been good and Iโ€™ve done fillers and itโ€™s been bad,โ€ she said in an interview with The Telegraph. โ€œIโ€™ve had to get them dissolved and Iโ€™ve been ridiculed relentlessly. And I have shed tears about it. Itโ€™s very stressful.โ€


What the actual f#ck is happening to our work?

โ€œWeโ€™re talking about women who spent decades building expertise that suddenly feels worthless in a market that wants cheaper, younger, faster, AI-generated, good enough.โ€

By Sheri Radel


Aging out of f#cks: The neuroscience of why you canโ€™t pretend anymore

The science of why you become less of a people-pleaser with age

By Ellen Scherr

Youโ€™re in a meeting. Someone says something objectively wrong. And instead of doing your usual dance โ€” the soft correction, the diplomatic phrasing, the careful preservation of everyoneโ€™s feelings โ€” you justโ€ฆ say it.

โ€œThatโ€™s not accurate.โ€

No cushioning. No apology. No emotional labor to make your truth more palatable.

And everyone looks at you like youโ€™ve grown a second head.


After Barnes & Noble acquisition, Emily McDowell enters her post-burnout reinvention period

The โ€œviralโ€ creative entrepreneur digs into her new path as a public speaker and consultant โ€” while enjoying time with her fiancรฉ and dealing with Long Covid

โ€œIโ€™m a formerly hard-charging GenXโ€™er who basically murdered myself and factory-farmed my creativity in an attempt to achieve my way into happiness. Shocker: it didnโ€™t work.โ€ โ€” Emily McDowell


6 women reveal their perimenopause symptoms and how they deal

By Sarah Nardi

A couple years ago, I approached my longtime physician to discuss perimenopause. At that point, Iโ€™d developed symptoms that were beginning to impact my life in measurably negative ways. Iโ€™ve always had a good relationship with my doctor, who is a woman, so when I sat down in her office, I was expecting a meaningful conversation.

What I got instead was the worldโ€™s tidiest Socratic dialogue:

Are you having hot flashes?

No.

Night sweats?

Outside of sporadic, obligatory sex? No.

Then youโ€™re not in perimenopause.

Boom. Case closed.


Claire Zulkey

Starring Claire Zulkey, freshly 46

Occupation: Writer and founder of Evil Witches

Location: Evanston, Illinois

Letโ€™s connect: Substack โ€ข zulkey.com

Howโ€™d you sleep?

I slept great last night. For once I listened to my better judgment and read a book (Health and Safety by Emily Witt) before I drifted off because I had just watched the NCAA menโ€™s championship with my kid and could tell I was screened out.


Dream job alert: Lโ€™Oreal Thompson Payton sells infertility memoir and opens bookstore

โ€œIโ€™m the happiest Iโ€™ve ever been personally and professionally and I strongly attribute that to finally leaning all the way into my God-given purpose.โ€

Lโ€™Oreal Thompson Payton is a book author, bookstore owner, freelance writer, and yoga instructor

Age: 38

Location: Evanston, Illinois

This article was originally published here in The Midst Substack, our free twice-weekly newsletter.


Spread the word about The Midst to your 40- and 50-something friends. We’re a collective of creatives, entrepreneurs, free spirits, and forward thinkers on a mission to get what we really want out of life.โ  Get our free newsletter here on Substack and follow us here on Instagram.

Amy Cuevas Schroeder is the founder of The Midst and The Midst Substack, the community platform helping women over 40 live healthy, inspired lives on their terms. Amy started her first business, Venus Zine, in her dorm room at Michigan State University, scaled the magazine to international distribution, and sold the company to a Chicago publisher a decade later. She now lives in the Phoenix area and is raising twin girls with her husband, Martin Cuevas, a psychotherapist at Therapy for Creativity. Between Venus and The Midst, she's worked as a content strategist for Writer AI, Etsy, Minted, Unusual Ventures, Atlassian, and Grow Therapy, and has written for TechCrunch, NYLON, Pitchfork, The Startup, West Elm, and more. As a serial contentpreneur, she specializes in creating meaningful content at scale, with thriving communities at the center. Amy now works as a startup advisor, perimenopause market expert and consultant to businesses. She is an SEO expert who scaled The Midst organic views to 700,000 in 2025. Subscribe to The Midst newsletter for exclusive content that you can't get on the-midst.com here on The Midst Substack. View Amy's content portfolio here.

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